Standardized to the WHO's Reference Reagent Recombinant Soluble Transferrin Receptor (rsTfR) (code: 07/202).

Kinetic UDR Immunoassay, enhanced with polystyrene particles, for their use on Beckman Coulter's IMMAGE® 800 Immunochemical Systems.

Immunoassay enhanced with polystyrene particles, for their use on Clinical Chemistry automatic analyzers.

Applications available for the most common analyzers of Clinical Chemistry. For example Advia®, Alinity C, AU®, Atellica™, cobas® C, Optilite® or Mindray among others.

Clinical Significance of Soluble Transferrin Receptor (sTfR)

sTfR is a good marker in the diagnosis of iron deficiency. The Joint WHO/CDC Technical Consultation on Assessment of Iron Status at Population Level (Geneva, April 2004) had concluded that measurement of both serum Ferritin (Ft) and sTfR provided the best approach for estimating the iron status of populations.

sTfR enables evaluation of erythropoiesis without the need for cytological study of the bone marrow, as long as iron deficiency is excluded. Thus, it is helpful in managing response to erythropoietin treatment (EPO), and it has also been proposed for use in anti-doping control.

sTfR, rsTfR, Iron Status at Population Level, Erythropoiesis, Erythropoietin treatment EPO, WHO code 07/202, IMMAGE ® Beckman Coulter, Advia ® Siemens Healthineers, Optilite ® The Binding Site, PENIA, TIA.