Standardized to the 1st British Standard for Human Serum Proteins (other than Immunoglobulins) (code: 74/520) of the National Institute for Biological Standards and Controls (a WHO Laboratory for Biological Standards).

Kinetic Non-competitive Nephelometric Immunoassay, for their use on Beckman Coulter's IMMAGE® 800 Immunochemical Systems.

Turbidimetric Immunoassay (TIA), for their use on Clinical Chemistry automatic analyzers.

Applications available for the most common analyzers of Clinical Chemistry. For example Advia®, Alinity C, AU®, Atellica™, cobas® C, Optilite® or Mindray among others.

Clinical Significance of the Hemopexin (HPX)

Hemopexin levels in serum reflect the amount of heme released into the blood. After the depletion of Haptoglobin, in episodes of acute hemolysis, Hemopexin intervenes, which causes further decline, which can even lead to depletion, indicative of the release of large quantities of the heme group. It is thus one of the diagnostic indicators of hemolytic anaemia and clearly reflects the severity of the hemolytic episode.

Reduction of Hemopexin levels is typically associated with a decrease in Haptoglobin except in Thalassemia where there is no significant reduction of Haptoglobin.

HPX, HPT, Haptoglobin, Hemopexin, Hemo, Thalassemia , WHO code 74/520, IMMAGE® Beckman Coulter, Optilite® The Binding Site, PENIA, TIA.